Plasma Proteome Project Pilot Phase 353

Beniam T. Berhane, ChenggongZong, David A. Liem, Aaron Huang, Steven Le, Ricky D. Edmondson, Richard C.Jones, Xin Qiao, Julian P. Whitelegge, Peipei Ping and Thomas M. Vondriska 17.1 Introduction 353

17.1.1 HUPO Plasma Proteome Project pilot phase 354

17.1.2 Need for novel insights into cardiovascular disease 354

17.2 Materials and methods 355

17.3 Groups of cardiovascular-related proteins 356

17.3.1 Markers of inflammation and CVD 356

17.3.2 Vascular and coagulation proteins 357

17.3.3 Signaling proteins 359

17.3.4 Growth- and differentiation-associated proteins 360

17.3.5 Cytoskeletal proteins 360

17.3.6 Transcription factors 361

17.3.7 Channel and receptor proteins 363

17.3.8 Heart failure- and remodeling-related proteins 364

17.4 Functional analyses and implications 365

17.4.1 Organ specific cardiovascular-related proteins in plasma 365

17.4.2 Novel cardiovascular-related proteins identified in plasma 366

17.5 Methodology considerations 368

17.6 Conclusions and future directions 368

17.7 References 370

Was this article helpful?

0 0
Your Heart and Nutrition

Your Heart and Nutrition

Prevention is better than a cure. Learn how to cherish your heart by taking the necessary means to keep it pumping healthily and steadily through your life.

Get My Free Ebook


Post a comment