Ascending Diffuse Modulatory Systems

The median forebrain bundle is one ofthe three diffuse modulatory systems that ascend in the brain stem (see Figs. 4 and 5). It contains neuronal fibers from neurons that release norepinephrine, serotonin, or dopamine as

FIGURE 2 The Papez circuit. The Papez circuit and related structures form a network that links emotional experiences and emotional expression. (A) Anatomic location of the Papez fiber tracts is shown in dark blue, the four relevant nuclei are shown in medium blue, and related structures are shown in gray. (B) Flow diagram of the Papez circuit; the areas of neuronal processing are depicted in ovals, and the connections are indicated by black arrows. Other related structures are shown in rectangles.

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