Clinical Note

Heart failure is a relatively common condition in which left aterial pressure is abnormally high. This is often caused by a depressed contractility. A number of diseases can lead to heart failure including hypertension, valve lesions, such as aortic or mitral regurgitation coronary atherosclerosis, or myopathic processes within the heart muscle. In patients with failure related to depressed contractility, the primary consequence is reduced stroke volume and inadequate cardiac output. The condition is often difficult to treat and the prognosis is poor for advanced cases. Cardiac transplantation has emerged as an effective treatment.

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