Maurice Goodman

Overview 720 The Testes 720

Control of Testicular Function 722 Leydig Cells 723 Germinal Epithelium 724 Testosterone 726

Secretion and Metabolism 726

Mechanism of Action 726

Effects on the Male Genital Tract 727

Effects on Secondary Sexual Characteristics 727

Sexual Differentiation 728

Development of Internal Reproductive Ducts and Their

Derivatives 728 Development of the External Genitalia 729 Postnatal Development 730 Regulation of Testicular Function 731

Gonadotropin-Releasing Hormone and the Hypothalamic

Pulse Generator 731 Negative Feedback Regulators 732 Prepuberty 733

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