Ho

estradiol-17ß

FIGURE 7 Metabolism of testosterone. Most of the testosterone secreted each day is degraded by the liver and other tissues by reduction of the A ring, oxidation of the 17 hydroxyl group, and conjugation with polar substituents. Conversion to 5a-dihydrotesto-sterone takes place in target cells catalyzed mainly by the type II dehydrogenase and in nontarget cells mainly but not exclusively by the type I dehydrogenase. Aromatization of testosterone to estradiol may occur directly or after conversion to androstenedione. Note that 5-a dihydrotestosterone cannot be aromatized or reconverted to testosterone.

Was this article helpful?

0 0
Get Rid of Gallstones Naturally

Get Rid of Gallstones Naturally

One of the main home remedies that you need to follow to prevent gallstones is a healthy lifestyle. You need to maintain a healthy body weight to prevent gallstones. The following are the best home remedies that will help you to treat and prevent gallstones.

Get My Free Ebook


Post a comment