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0 20 40 60 80 100 120 140 160 180 200 220 240 Heart rate (beats per minute)

FIGURE 9 The heart rate is varied by electrical pacing and the effect on cardiac output is plotted. Note that cardiac output is relatively insensitive to changes in rate within the physiologic range, but cardiac output falls dramatically at both the high and low extremes.

0 20 40 60 80 100 120 140 160 180 200 220 240 Heart rate (beats per minute)

FIGURE 9 The heart rate is varied by electrical pacing and the effect on cardiac output is plotted. Note that cardiac output is relatively insensitive to changes in rate within the physiologic range, but cardiac output falls dramatically at both the high and low extremes.

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