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FIGURE 3 Effects of carbon monoxide (CO) and anemia on blood-O2 equilibrium curves. Anemia (7.5 g/dL total hemoglobin) decreases O2 concentration but does not change the shape of the curve. CO poisoning (7.5 g/dL hemoglobin available for O2 binding) decreases O2 concentration and shifts the curve to the left. Pvo2 must decrease to maintain the arterial-venous O2 concentration difference for a given Pao2 with CO. (After Roughton, Chap. 31 in Fenn and Rahn, eds., Handbook of physiology, Section 3, Respiration. Bethesda, MD: American Physiological Society, 1964.)

FIGURE 3 Effects of carbon monoxide (CO) and anemia on blood-O2 equilibrium curves. Anemia (7.5 g/dL total hemoglobin) decreases O2 concentration but does not change the shape of the curve. CO poisoning (7.5 g/dL hemoglobin available for O2 binding) decreases O2 concentration and shifts the curve to the left. Pvo2 must decrease to maintain the arterial-venous O2 concentration difference for a given Pao2 with CO. (After Roughton, Chap. 31 in Fenn and Rahn, eds., Handbook of physiology, Section 3, Respiration. Bethesda, MD: American Physiological Society, 1964.)

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