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FIGURE 11 Effects of ACh on SA nodal cells. ACh hyperpolarizes nodal cells; thus, it takes a longer time for the pacemaker potential to reach threshold. The rate of rise of the pacemaker potential is also slowed. Consequently, the interval between action potentials is increased. (Modified from Katz AM. Physiology of the heart. New York: Raven Press, 1992.)

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FIGURE 11 Effects of ACh on SA nodal cells. ACh hyperpolarizes nodal cells; thus, it takes a longer time for the pacemaker potential to reach threshold. The rate of rise of the pacemaker potential is also slowed. Consequently, the interval between action potentials is increased. (Modified from Katz AM. Physiology of the heart. New York: Raven Press, 1992.)

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