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Nerve growth factor (NGF)

Leukemia inhibitory factor (LIF)

there are sufficient similarities in their modes of signal transduction to consider them as a group. These receptors rely on physical association between proteins (protein-protein interactions) and trigger formation of large aggregates of proteins to transmit the signal.

The tyrosine-kinase-dependent receptors have only a single membrane-spanning region and a seemingly less complex architecture than the G-protein receptors. The

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