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FIGURE 16 Changes in plasma IGF-I and growth hormone concentrations in the peripubertal period in normal boys. Bars in the lower panel indicate 24-hr integrated concentrations of GH. The blue curve is the idealized growth velocity curve for North American boys. (Upper panel from Juul A, Dalgaard P, Blum WF, Bang P, Hall K, Michaelsen KF, Muller J, Skakkebaek NE, J Clin Endocrinol Metab 1995; 80:2534-2542; lower panel from Martha PM, Jr, Rogol AD, Veldhuis JD, Kerrigan JR, Goodman DW, Blizzard RM, J Clin Endocrinol Metab 1989; 69:563-570. With permission.)

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