Copyright © 2004, Elsevier Science (USA) All rights reserved.

Resting potentials are characteristic features of all cells in the body, but nerve cells and other excitable cells, such as muscle cells, not only have resting potentials but are capable of altering these potentials for the purpose of communication, in the case of nerve cells, and for the purpose of initiating contraction, in the case of muscle cells. The material that follows introduces the ionic mechanisms that endow excitable membranes with this ability.

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