FIGURE 2 The basal ganglia motor loop. Major connections linking motor cortex, basal ganglia (blue box), and thalamus are shown in this simplified scheme. Cortical areas representing all three levels of the motor hierarchy project to the neostriatum (caudate and putamen). Output from the basal ganglia is via the globus pallidus and substantia nigra to three nuclei of the thalamus. The thalamus completes the loop pathway with projections back to the motor cortex, particularly the supplemental motor area.

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