In this case, therefore, after intravenous injection into the plasma, it remains within the vascular bed at least for the time necessary to achieve a uniform distribution (Fig. 5A). A substance commonly employed for this purpose is serum albumin labeled with radioactive iodine (I-albumin).

Example: An amount of 131I-albumin having 350,000 counts per minute (cpm) is injected intravenously. One hour later, 10 mL of whole blood are withdrawn and centrifuged. The whole blood consisted of 5.5 mL of plasma and 4.5 mL of packed blood cells. Then, 1 mL of the plasma is removed and found to contain 100 cpm. Thus,

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