Secondary Active Reabsorptive Processes

In addition to HCO^, several other solutes are actively reabsorbed in the proximal tubules. Most of these are organic substrates such as glucose, amino acids, and other organic acids that must be reclaimed and returned to the blood for utilization by the mills of metabolism. As in the intestine, these active transport processes are driven not by the direct expenditure of energy, but by coupling to the Na+ electrochemical potential gradient. A vast quantity of Na+ is reabsorbed in the proximal tubule, and in the process it diffuses

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