Lytic bacteriophages are viruses that can infect and kill bacteria. Their use for the prevention and treatment of infectious disease offers another attractive alternative to antimicrobials, because they are highly specific to a bacterial species, are nontoxic to the animal host, and can increase in titre as they infect and kill their target bacteria. In experimentally infected animals, bacte-riophages have been shown to prevent and treat E. coli induced diarrhea in calves, piglets, and lambs, and to prevent E. coli respiratory infections in broiler chick-ens.[15,16]
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