Bovidae Cattle Sheep Goat And Their Relatives

In these species, the trophectoderm (outer) cells of the conceptus begin to produce an antiluteolytic protein factor called interferon-tau (IFN-t) at the blastocyst stage of development. Synthesis becomes maximal as the conceptus elongates in the period immediately preceding attachment of trophectoderm to the uterine wall.[5]

The progenitor IFN-t gene duplicated from an IFN-o gene approximately 36 million years ago (MYA). As a consequence, this gene family is unique to the Ruminantia suborder.[9] IFN -t is expressed prior to the release of luteolytic pulses of PGF2a from the endometrium[10] and abrogates PGF2a release by downregulating transcription of the estrogen and oxytocin receptor genes in the uterine endometrium.[4,6,8,10] IFN -t may simultaneously promote production of prostaglandin E2 (PGE2), which has a luteotrophic rather than luteolytic action on the CL and exerts a local immunosuppressive action at the maternal conceptus interface.[5]

How To Bolster Your Immune System

How To Bolster Your Immune System

All Natural Immune Boosters Proven To Fight Infection, Disease And More. Discover A Natural, Safe Effective Way To Boost Your Immune System Using Ingredients From Your Kitchen Cupboard. The only common sense, no holds barred guide to hit the market today no gimmicks, no pills, just old fashioned common sense remedies to cure colds, influenza, viral infections and more.

Get My Free Audio Book

Post a comment