Responses to microbial feed additives and enzymes in farm animals are often small and often highly variable. Much of this variability is due to differences between products; even the same microbial strain grown under different conditions will have different effects. However, as progress is made in defining the mode of action of these additives, predicting dietary situations in which they may be beneficial should be possible. Indeed, as we learn more about the mode of action of the current products, strategies for the development of new additives with enhanced and more reliable activities could be devised.

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