Exogenous ST treatment of domestic animals markedly improves production efficiency by increasing the amount of lean meat or milk produced per unit of feed intake. As a result, ST is used commercially in the dairy and swine industries in many countries. The mechanisms involve coordinated changes in the physiological processes, and many of these adaptations involve changes in tissue response to homeostatic signals. Overall, these orchestrated adaptations allow for a greater partitioning of nutrients for lean tissue accretion (during growth) or milk synthesis (during lactation), thereby allowing for increases in performance and productive efficiency while preserving animal well-being.

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