Confidence Interval Of Qtl Map Location And Highresolution Mapping Of

QTL mapping gives the most likely point location for the QTL, accompanied by a confidence interval, which is an interval along the chromosome to both sides of the point location within which the QTL could actually reside. The width of this interval defines the map resolution of the experiment. In many QTL mapping experiments, the confidence interval is very large, from one-quarter to one-half of the entire chromosome.

The confidence interval can be reduced by increasing the sample size and the density of marker spacing, and by application of specialized multilocus and multitrait mapping procedures. Advanced intercross lines can also be used to improve map resolution in experimental and farm populations.

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