Growthrelated Transgenes

Early transgenic farm animal research was inspired by the dramatic growth of transgenic mice that expressed a growth hormone (GH) transgene.[1] A number of transgenic pigs and sheep were subsequently produced with human, bovine, rat, porcine, or ovine GH under the control of several gene promoters.[2] Although pigs expressing GH transgenes grew faster, utilized feed more efficiently, and were much leaner than their nontrans-genic siblings, they were not larger and exhibited several notable health problems, which included lameness, susceptibility to stress, gastric ulcers, and reproductive prob-lems.[2] The GH transgenic lambs did not grow faster or utilize feed more efficiently than control lambs, but they were much leaner and had serious health problems.[2]

More recently, an insulin-like growth factor-I (IGF-I) transgene has been used to produce transgenic pigs with enhanced muscle development and reduced fat in the carcass, but the transgene did not improve growth rate or feed efficiency. In contrast to the GH transgenic pigs, definitive phenotypes for the IGF-I transgenic pigs were not detected, and no gross abnormalities, pathologies, or health-related problems were encountered.[3]

Supplements For Diabetics

Supplements For Diabetics

All you need is a proper diet of fresh fruits and vegetables and get plenty of exercise and you'll be fine. Ever heard those words from your doctor? If that's all heshe recommends then you're missing out an important ingredient for health that he's not telling you. Fact is that you can adhere to the strictest diet, watch everything you eat and get the exercise of amarathon runner and still come down with diabetic complications. Diet, exercise and standard drug treatments simply aren't enough to help keep your diabetes under control.

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