Improving Generation and Propagation of Transgenic Livestock

Transgenic technology developed to add genes has been widely applied to livestock species because it is technically simple, although it is inefficient. Not all injected eggs will develop into transgenic animals, and then not all transgenic animals will express the transgene in the desired manner. Characterizing a transgenic line of livestock is a slow and expensive business. Nuclear transfer would speed the expansion of a successful transgenic line, but perhaps more important it would allow more efficient generation of transgenic animals in the first place. Foreign DNA could be introduced into cell lines in culture, and cells containing the transgene in the correct configuration could be grown and used as a source of nuclei for transfer, ensuring that all offspring are transgenic.[11-13]

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