Metabolic diseases or disorders result from an imbalance between dietary supply of specific nutrients and the high demand of the nutrients for productive purposes. Production may proceed using body stores, however, an imbalance occurs when there is an inability of tissues to adapt to the increased requirement in conjunction with either a decreased or limited intake. Two nutrients that have elaborate homeostatic mechanisms to maintain relatively stable plasma concentrations are glucose and calcium. There are several common disorders that relate, in part, to metabolism of these two nutrients.
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