The corpus luteum is the dominant structure during most of the estrous cycle. The luteal phase is measured from ovulation until regression of the corpus luteum (luteoly-sis). Following ovulation, the corpus luteum forms from the ruptured follicle and can be observed until day three as a corpus hemorrhagicum. About day three to five, the corpus luteum loses its bloody appearance, increases in size, and produces sufficient progesterone to be detected in peripheral circulation.1-1-1 By approximately midcycle, the corpus luteum reaches maximum size and secretion of progesterone (Fig. 1).
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