Treatment of lactating cows with ST results in an increased synthesis of all milk constituents consistent with the increase in milk yield. The mechanism involves both an increase in the synthetic capacity and an improved maintenance of mammary epithelial cells. Coordinated increases in mammary blood flow and mammary uptake of nutrients also occur. The increased milk synthesis is supported by a series of orchestrated changes in other body tissues to ensure that the mammary gland is supplied with the quantity and pattern of nutrients to support milk synthesis.[10,11,13] These coordinated adaptations involve most tissues in the body, a portion of which is illustrated in Table 1.
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