Injecting PGF2a at the end of a short-duration (7 days) progestin treatment allows estrus in nearly all females to be synchronized during a shorter treatment period. Administering progestin for approximately seven days allows any female in estrus or metestrus at the outset to advance to the luteal phase before PGF2 a is administered. Expression of estrus is prevented in the remaining females that are in proestrus or late diestrus by the progestin treatment, and those in the luteal phase respond to the injection of PGF2a Therefore, the combination of both hormones shortens the overall period of treatment and generally allows normal fertility.1-3-1
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