Riboflavin

This vitamin is relatively labile, being reduced in bioactivity by light, alkali, and oxygen. In feedstuffs, it exists primarily as nucleotide coenzymes, in which form the bioavailability is probably less than 100%. Chung and Baker[13] estimated that riboflavin bioavailability in a corn-soybean meal diet is 60% for chicks relative to crystalline riboflavin. Gadient[14] suggested that 95 100% of riboflavin bioactivity in pelleted feeds remains following storage for 3 mo at room temperature.

Sauberlich[12] suggested that several factors may reduce the bioavailability of riboflavin in foods. Among the suggested factors antagonizing riboflavin were excess dietary levels of tetracycline, Fe, Zn, Cu, ascorbate, and caffeine. Patel and Baker[15] used chick growth bioassays to evaluate dietary excesses of Fe (420 mg/kg), Zn (448 mg/kg), Cu (245 mg/kg), ascorbic acid (1000 mg/kg), caffeine (200 mg/kg), and chortetracycline (500 mg/kg), which were added to riboflavin-deficient soy-isolate semipurified diets. None of these supplements was found to decrease the utilization of crystalline riboflavin.

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