Sperm Mediated Gene Transfer

The simplest, but most controversial, method of gene transfer involves merely mixing a transgene with spermatozoa and using them to fertilize oocytes, either in vitro or by artificial insemination. The use of sperm-mediated transfer in mice by Dr. Lavitrano[8] was initially discounted as unrepeatable by many investigators. During the past decade, research on this procedure has persisted and many investigators report successful gene transfers by this technique. Unfortunately, only a few studies have provided convincing evidence that the transgene was unaltered before or during the integration process and capable of expressing appropriately in the resulting transgenic animals.[9]

100 Pregnancy Tips

100 Pregnancy Tips

Prior to planning pregnancy, you should learn more about the things involved in getting pregnant. It involves carrying a baby inside you for nine months, caring for a child for a number of years, and many more. Consider these things, so that you can properly assess if you are ready for pregnancy. Get all these very important tips about pregnancy that you need to know.

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