Antidepressants

■ Tricyclic antidepressant

■ Associated with fetal cardiac anomalies

■ No increased risk of major malformations or developmental abnormalities has been observed.

Tranquilizers

■ Chlordiazepoxide (Librium) is associated with congenital anomalies.

■ Diazepam use perinatally has been associated with fetal hypothermia, hypotonia, and respiratory depression.

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