Diagnosis

■ Physical exam may reveal multiple bleeding points associated with purpura and petechiae.

■ Lab evaluation reveals thrombocytopenia, hypofibrinogenemia, an elevated prothrombin time, and increased fibrin split products.

Pregnancy normally induces:

■ Increases in coagulation factors I (fibrinogen), VII, VIII, IX, and X

■ Increased activation of platelet clotting

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