Genetic Testing

Genetic testing, if indicated, is performed with the following techniques:

FISH (fluorescent in situ hybridization): A specific DNA probe with a fluorescent label that binds homologous DNA ^ allows identification of specific sites along a chromosome

Karyotyping: Allows visualization of chromosome size, banding pattern, and centromere position


■ Advanced maternal age

■ Previous child with abnormal karyotype

■ Parental chromosome rearrangements

■ Fetal structural abnormality on sonogram

■ Unexplained intrauterine growth retardation (IUGR)

■ Abnormally low MSAFP

The fetal head is normally larger than the body in T2 and early T3.


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