Sepsis

• Reduced conscious level may compromise airway

• Oxygen therapy is needed

• Hypoperfusion and hypoxaemia increase the respiratory rate

• Pneumonia can be the cause of severe sepsis C

• Hypovolaemia requires successive fluid challenges

• Vasopressors may be needed because of an abnormally low SVR

• Reduced myocardial contractility may also require treatment

• Clotting abnormalities need correcting

D and E

• Full examination is required to locate the source of inflammation, including microbiological screening and imaging

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