Benzoyl peroxide is commonly associated with local irritation that presents as erythema, peeling, dryness, burning, stinging, itching and soreness. Use of an emollient or water-based gel may reduce these reactions. Allergic contact dermatitis, characterised by erythema, small papules and pruritus, may occur rarely. RCT evidence shows that the side-effect profile of a 2-5% preparation is similar to that of 5%53,59 and less than 10% preparations.53 Combinations of benzoyl peroxide with antibiotics are unstable because of degradation of the antibiotic by benzoyl peroxide. Benzoyl peroxide will bleach hair and fabrics and patients should therefore be counselled accordingly. It is safe for use during pregnancy. There have been concerns that benzoyl peroxide may promote skin cancer62,63 but these have been refuted.64
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Rosacea and Eczema are two skin conditions that are fairly commonly found throughout the world. Each of them is characterized by different features, and can be both discomfiting as well as result in undesirable appearance features. In a nutshell, theyre problems that many would want to deal with.