Heredity is important. It has been recently shown that 20% of the children with steroid rosacea had at least one close blood relative with rosacea. Fair complexion, blond hair and green/blue eyes are characteristic of patients with rosacea. In England, for example, 48% of patients with rosacea had this skin type. How this frequency compares with that of the general British population is not known. About 0-1% of coloured people are also affected by rosacea, as reported by an old American observation. Rosacea occurs more frequently in women than in men (3:1).
Typically, rosacea is a multistage disease and the prevalence may change according to the stage/s at which the diagnosis is made. The stages are the flushing stage or transitory congestive redness, the erythrosis stage or persistent teleangiectatic redness, the papulopustular stage and the phyma stage. Only a minority of patients with the first two stages of the disease progress to the papulopustular stage and even fewer to the phyma stage. The condition appears more often in middle age, although this varies for the stages of the disease: erythrosis develops earlier (mean age in 1979: 34 years), whilst phymas develops later (mean age 66 years).
The aetiopathogenesis of papulopustular rosacea is controversial and it is unclear why a patient proceeds from stages that are mainly functional to those that are inflammatory. The immune system, with both its cell-mediated and humoral arms, may be involved. Indeed, antibodies directed against collagen VII, the elastotic tissue and the Demodex folliculorum mite have been detected. However, the production of antibodies may be a secondary event or the elastotic tissue and D. folliculorum may simply represent the structures where antibodies accumulate spontaneously ("beach effect"). In addition, Helicobacter pylori, a gramnegative bacterium, has recently been hypothesised to play a role. Opinions diverge on its association with rosacea, but drugs that eradicate H. pylori were used to treat papulopustular rosacea long before the issue of H. pylori arose.
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Rosacea and Eczema are two skin conditions that are fairly commonly found throughout the world. Each of them is characterized by different features, and can be both discomfiting as well as result in undesirable appearance features. In a nutshell, theyre problems that many would want to deal with.