We have found no systematic reviews. Versus placebo
We have found 10 RCTs comparing various concentrations of topical minoxidil with placebo. Early reports suggested a significantly increased frequency of regrowth in patchy but not total alopecia areata,28-34 although subsequent RCTs failed to confirm these results.35,36
This incompletely reported study suggested that there was a higher response rate to 5% minoxidil than to 0-005% betamethasone dipropionate. Both were said to be superior to placebo but strict numbers and statistical analysis were not reported.37
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