Benefits

There is no systematic review. Besides a small RCT that demonstrated the efficacy of 200 units of botulinum toxin A (Dysport),12 two large

RCTs have demonstrated the efficacy of this treatment in axillary hyperhidrosis. Heckmann et al.6 investigated the efficacy of botulinum toxin A 200 units (two-fifths of a vial Dysport) in 145 participants with axillary hyperhidrosis. After 2 weeks the rate of sweating was reduced below 25 mg/minute in 64-8% of the axillae treated with botulinum toxin compared with 1-4% of the axillae treated with placebo. At least 50% reduction in sweating (compared with baseline) could be achieved in 134/145 of the axillae treated with botulinum toxin and 22/145 of the axillae treated with placebo. Based on this data, the numbers needed to treat (NNT) can be calculated as 1-3 to 1 (i.e. from four patients treated with 200 units Dysport, three patients will obtain at least a 50% reduction in sweating). In another RCT, 320 patients with axillary hyperhidrosis were treated with 50 units of a different strain of botulinum toxin A (half a vial of Botox). After 3 weeks, 95% (95% confidence intervals 91-5 to 97-4) in the active-treatment group and 32-1% (21-9, 43-6) in the placebo group reported at least a 50% reduction in sweating.7 Based on this data the NNT for 50 units Botox can be calculated as 1-7 to 1 (of four patients treated, two would obtain at least a 50% reduction in sweating).

11 Habits To Make or Break For Soft Flawless Skin

11 Habits To Make or Break For Soft Flawless Skin

Habits to Break and Habits to Maintain for Dazzling Skin. As you all know, our skin is the obvious appearance of who or what we are, or perhaps would like to be. However, it is more than just a simple mask.

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