There are no good RCTs demonstrating the efficacy of botulinum toxin A for palmar hyperhidrosis. Two RCTs, one of Dysport 120 units and of Botox, comparing 50 units versus 100 units, had significant flaws in the design or analysis of the study.19,20 Therefore evidence is based on case series. The largest case series comprise 23 patients treated with Botox 50 units (half a vial)21 and 21 patients treated with Dysport 240 units (approximately half a vial) per hand.22 Vadoud-Seyedi et al.21 reported "significant improvement". Schnider et al.22 reported a median reduction of sweat production, as measured by the ninhydrin test, of 42% compared with the baseline values. The median overall satisfaction was "very good".
Was this article helpful?
Not Too Happy With Your Dull, Lifeless Skin? Do You Get Self-Conscious About Your Looks Especially The Evening You Need To Attend A Party? Are You Frustrated With Your Futile Attempts To Get Back Your Once-Glowing Skin? Fret Not Finally Discover How You Can Bring In A Natural Glow To Your Skin And Uncover Super Effective Tips And Strategies To Enliven Your Looks Once Again Enjoy A Perfectly Healthy Skin That Breathes With HappinessAnd Make Every Head Turn To Take A Second Look At You