A study of patch tests and drug reactions showed only two patients among 22 SJS/TEN cases with a relevant positive test: one with sulphonamide and one with phenobarbital. Healthy volunteers were used as controls.41 In a series of 14 patients, seven patch tests were performed, three of which were positive (ethylbutylmalonylureum, phenazone, phenylbutazone). Among the four negative tests, three intracutaneous tests were performed, two of which were positive (phenacetine, chloramphenicol).7

We found only case reports and no clinical trial about in vitro tests (essentially lymphocyte transformation tests).

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