Childhood alopecia areata

• In most RCTs an early age of onset is an adverse prognostic factor for regrowth.

• Topical corticosteroids therapy may be more effective in children than in adults.

• Intralesional injection of corticosteroids is unsuitable for use in children. Most children will not tolerate repeated injections, limiting the usefulness of intralesional corticosteroids.

• Prolonged therapy with oral corticosteroids may retard growth, demineralise bones, and lead to premature fusion of the bony epiphyses.

• PUVA is contraindicated in children because of the possible increase in risk of future development of melanoma.

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