Barnard Health Care

Combination therapy

Acne No More Ebook

Get Instant Access

A number of RCTs have investigated oral and topical antibiotics either against or in combination with other agents, (see Web Table 13.9) the rationale for this being that treatments that attack more than one factor implicated in the pathogenesis of acne will be more effective. The different mechanisms of action are summarised in Table 13.4.

Table 13.4 Targets of acne therapies (adapted from Gollnick160)

Sebum excretion Keratinisation Follicular P. acnes Inflammation

Table 13.4 Targets of acne therapies (adapted from Gollnick160)

Sebum excretion Keratinisation Follicular P. acnes Inflammation

+++, very strong effect; ++ strong effect; + moderate effect; (+) Indirect/weak effect; - no effect

+++, very strong effect; ++ strong effect; + moderate effect; (+) Indirect/weak effect; - no effect

Was this article helpful?

Acne Attack

This Book Below Will Show You Exactly What You Need To Beat Your Acne!

Get My Free Ebook