Comment

One RCT60 described the method of randomisation using a table of random numbers, but was not blinded. Triamcinolone acetonide, 2-5 mg, was used in this study, but whether larger doses of steroid might be effective remains unknown. The other two RCTs58,59 were described as randomised but only one59 was double blind). In this latter RCT, scaling and pruritus were eliminated more quickly in the group that used erythromycin and prednisone in addition to griseofulvin but the authors think this may have been due to the smaller volume of the kerions in this group rather than the effects of therapy, so that the patients became symptom free sooner.

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