Comment

Zidovudine alone is no longer standard therapy for HIV infection, and the advent of HAART has changed the clinical course of AIDS-related KS. The effectiveness of interferon combined with HAART is unknown. No randomised trials have compared liposomal anthracyclines with interferon in early AIDS-related KS. The effectiveness of interferon combined with cytotoxic chemotherapy is unknown. All of the above trials compared two or more actives or different doses of interferon and therefore may be comparing several ineffective treatments. None of these trials was placebo controlled.

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