We have very limited information on PLE prognosis, and this one well-conducted follow up study11 involved a selected group of patients - those assessed in a hospital department, and willing to attend for review. Our experience in Dundee (based on another severely affected patient group) is that a substantial proportion of those with PLE severe enough to require repeated yearly prophylactic phototherapy do, after several years, experience resolution, or marked improvement, so that they can then stop attending for treatment.22 We do not know whether this is spontaneous resolution, or whether it is a result of repeated phototherapy courses.

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