There is some reservation about the validity of pooled data from the different RCTs because of the generally low quality of trials and the heterogeneity of their design and methodology. For instance, different RCTs used slightly different topical SA products and while some RCTs included patients with refractory warts, others
How effective are the various available local treatments for clearing warts and what are the side-effects of these treatments?
excluded them. Despite this we feel there is good evidence for a modest but definite beneficial clinical effect of SA in treating ordinary warts.
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