A comparison of methotrexate with retinoid therapy might help to establish whether there is a place for the former in this disease, the ideal therapy for which remains elusive.
We found no RCT of treatments for this uncommon but disabling pustular form of psoriasis, which can cause marked destruction of fingernails, toenails and surrounding tissues. The greatest number of published case reports in which successful response to treatment is claimed is for ciclosporin, although acitretin, methotrexate and dapsone have been reported in individual case reports to produce resolution.
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Do You Suffer From the Itching and Scaling of Psoriasis? Or the Chronic Agony of Psoriatic Arthritis? If so you are not ALONE! A whopping three percent of the world’s populations suffer from either condition! An incredible 56 million working hours are lost every year by psoriasis sufferers according to the National Psoriasis Foundation.