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Although 83 patients were involved, 245 superficial BCCs were included in the study, indicating more than one lesion per patient. Concealment of allocation was clear and analysis was carried out by intention to treat; however, no sample size calculation was included.

A further ongoing randomised trial aims to compare the efficacy of 5-ALA PDT following minimal debulking curettage with surgery for low-risk nodular BCCs and to compare pain and morbidity experienced by patients undergoing each procedure.33

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