The diagnosis of amyopathic dermatomyositis is confirmed by clinical-pathological correlation. The pattern of the skin disease is relatively characteristic and when an interface dermatitis is demonstrated on skin biopsy the diagnosis may be relatively firm. Classically, the diagnosis of dermatomyositis is confirmed by the presence of typical muscle symptoms and findings, together with elevated muscle enzymes, or an abnormal EMG and/or an abnormal muscle biopsy. Magnetic resonance imaging is becoming widely available and abnormalities of this test might be useful in diagnosis.
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