Do the outcomes make sense to me

First, some things to watch out for. Even though you might have specified which outcomes would change your practice in your structured evidence-based question, for example "proportion of patients cleared at 6 months", very often the studies will contain a number of other short-term outcomes.12 You then have to decide whether these outcomes provide useful clinical information. In most circumstances, there will be at least some information that makes some clinical sense to you.

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