In these trials, two of the 21 patients had increased triglyceride and/or creatinine levels (both received 3 mg/kg/day). In long-term treatment for psoriasis (more than 6 months) 6-18% of patients interrupted the treatment because of side-effects. The most serious side-effects were high blood pressure, renal toxicity and a potential increase in the risk of cancer.18 High blood pressure was reported in 5-26% of patients in short-term trials. Renal toxicity from ciclosporin is attributed to a vasoconstrictor effect on kidney arteries.18 Acute renal side-effects improve after withdrawal of treatment. However, renal impairment from long-term treatment could be irreversible.

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

Get My Free Ebook

Post a comment