Large tumours, or tumours in cosmetically complex areas such as near the eyelids or ears, often require an involved flap or graft technique for repair. The subsequent scar from surgical excision usually results in a hypopigmented line, and hypertrophic and keloidal changes may occur. SCC excision also requires removal of underlying fat as well as the tumour, which may disrupt normal vasculature, lymphatics or innervation. Since the surgical site is closed at the time of surgery and histology is performed on fixed tissues, the discovery of residual tumour may necessitate further surgical interventions.
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