Excision with narrow surgical margins can often be performed in an out patient setting, whereas larger margins may require skin grafting and in patient treatment. The Word Health Organization Study demonstrated that skin grafting could be reduced by 75% with the 1 cm versus the 3 cm margins.15 Some concern was expressed in the Intergroup Trial as three patients developed local recurrence as a first sign of relapse, all of whom had undergone a 1 cm excision margin for primary lesions between 1 mm and 2 mm in thickness.16
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